(an tee pye' reen) (ben' zoe kane)

Brand Name(s): A/B Otic Drops (as a combination product containing Antipyrine, Benzocaine)§, Auralgan^® (as a combination product containing Antipyrine, Benzocaine)§, Aurodex^® (as a combination product containing Antipyrine, Benzocaine)§

WHY is this medicine prescribed?

Antipyrine and benzocaine otic is used to relieve ear pain and swelling caused by middle ear infections. It may be used along with antibiotics to treat an ear infection. It is also used to help remove a build up of ear wax in the ear. Antipyrine and benzocaine are in a class of medications called analgesics. The combination of antipyrine and benzocaine works by reducing pain and discomfort in the ear.

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

HOW should this medicine be used?

Antipyrine and benzocaine otic comes as a solution (liquid) to place into the ear. When antipyrine and benzocaine is used to relieve ear pain, it is usually used every 1 to 2 hours as needed. When antipyrine and benzocaine is used to help in the removal of ear wax, it is usually used 3 times daily for 2-3 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use antipyrine and benzocaine otic exactly as directed.

Antipyrine and benzocaine otic is for use only in the ears.

To use the eardrops, follow these steps:

1. Hold the bottle in your hand for 1 or 2 minutes to warm the solution.
2. Place the prescribed number of drops into your ear.
3. Be careful not to touch the tip to your ear, fingers, or any other surface.
4. Moisten a small piece of cotton with the drops and insert into the outer ear.
5. Repeat steps 2-4 for the opposite ear if necessary.

What SPECIAL PRECAUTIONS should I follow?

Before using antipyrine and benzocaine otic,

• tell your doctor and pharmacist if you are allergic to antipyrine or benzocaine or any other medications.

• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while using antipyrine and benzocaine otic.

• tell your doctor if you have a hole in your ear drum(s) or ear tube(s). Your doctor will probably tell you not to use this medication.

• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using antipyrine and benzocaine otic, call your doctor.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do IF I FORGET to take a dose?

This medication is usually used as needed. If your doctor has told you to use antipyrine and benzocaine otic regularly, use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use extra solution to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Antipyrine and benzocaine otic may cause side effects. Call your doctor if you have any unusual problems while taking this medication.

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze. Antipyrine and benzocaine otic should be disposed of 6 months after the bottle is opened.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

What should I do in case of OVERDOSE?

If someone swallows antipyrine and benzocaine otic, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What OTHER INFORMATION should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

^§ These products are not currently approved by the FDA for safety, effectiveness, and quality. Federal law generally requires that prescription drugs in the U.S. be shown to be both safe and effective prior to marketing. Please see the FDA website for more information on unapproved drugs (http://www.fda.gov/AboutFDA/Transparency/Basics/ucm213030.htm) and the approval process (http://www.fda.gov/Drugs/ResourcesForYou/Consumers/ucm054420.htm).

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS^® Patient Medication Information™. © Copyright, 2024. The American Society of Health-System Pharmacists^®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: October 15, 2023.